Our bodies naturally produce proteolytic systemic enzymes, but with age we produce less. Systemic enzymes are proteolytic such as papain, bromelain, and others that are helpful in collapsing and destroying proteins. Most proteins in the body are beneficial, but some like Circulating Immune Complexes (CICs), are a leading cause of joint pain, arthritis pain and inflammation. The systemic enzymes nullify CICs, allowing the body to naturally repair itself.